There's a book called Extinction Point, and the premise is most of the population of the Earth dies off after a msyterious red rain falls from the Earth. Our hero, Emily, manages to contact some other survivors in a remote area of Alaska. Emily decides the best course of action in this case is to bike her way from New York all the way to this remote location in Alaska. She never learned to drive, which isn't unrealistic for someone in New York, but she grew up in the midwest in a small farming community. I can believe the extinction level event, but living in rural America without ever learning how to drive a car? No. You need to explain that. The worst part is that strange alien lifeforms, some of them dangerous, start bursting from the various corpses laying about the city. Still going to bike your way to Alaksa? Yup. That's the plan.