Hasn't been an issue yet, but good advice I'll keep in mind should I ever need it.
My remote group is a wisecracking bunch of smartarses - not a lot of side conversation, but it keeps the memes and image reactions from obscuring the rolls by overfilling the text buffer.
They're also scenery chewers... but they're fun, often surprising, and most always entertaining. I do miss sitting in the same room with them, but not enough to move back to Alaska.
And I'll note: I don't use sound effects often, and almost never music, be it FTF or online.
My choice of VTT (chosen because it costs nothing - GTove) has no sound support, so I use Discord for voice. I have, at times, put hold music on using a bot that linked to Youtube... but not recently.
My normal setup for game:
Desktop Computer: running the die roller, and GTove, and discord. Discord on the main game channel for dice rolls, same channel is used to send handouts and GM chosen illos.
Phone: voice login on speaker. Off Topic thread in text.
Laptop: when needed, logged in with a separate (serverless) account, sometimes logged into GTove, with several applications running. One of which is a D&D Cyclopedia treasure generator, coded in QB64; I need to recompile it for linux now. Another is my notes file in libre office, which also includes XP tracking. Discord on a private text channel for GM die rolls. Also, rules PDFs when needed.
Dead Tree Notebook: needed tables for the game. paper for HP tracking.
I'll note as well, the d2c3 roller is really good for FFG Star Wars, Genesys, and L5R5. Better than I can do.
My diceroller is written in Python, using discord.py. It works, very basic. I don't quite understand all the discord side of it, but it works.