Like I said, even with my realism-hat on I have no problem with a magic tricked-out wheelchair that can compensate for a some aspects of disability or even overcompensate to provide better abilities in some areas than non-disabled people. I am reminded of "Dalek", an episode in the first season of the rebooted Doctor Who series, where the eponymous Dalek is chasing some people, and they take to the stairs to escape... futilely as it turns out, as the Dalek starts screaming "ELEVATE!" and flies after them.
The issue, to whatever degree I have one, is with essentially making a wheelchair a cosmetic choice without any effect on your abilities at all – particularly a non-magical one.
As someone who is not himself disabled and as such might not be the best judge, I would look to Avatar: the Last Airbender for a good example of a character who is disabled and yet exceedingly competent: Toph Beifong. Toph is blind. However, she is also a very powerful earthbender, and she can use her earthbending as a very precise version of what D&D would call Tremorsense. This negates a lot of the disadvantages of being blind, but not all of them. She has no sense of color, she can't perceive things in the distance or things that fly (or much of anything if she herself doesn't have contact with the ground), and a light person moving softly can evade her senses. But on the other hand, she can sense things that are normally hidden, and she's just as able to move around in the dark as in light.
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